Photodynamic therapy can be effective as a treatment for herpes simplex labialis
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Photomedicine and Laser Surgery
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Background Data and Objective: Herpes is a common infectious disease that is caused by human herpesviruses.
Several treatments have been proposed, but none of them prevent reactivation of the virus. This article describes the use of photodynamic therapy (PDT) as a treatment for herpes lesions, and reports on four cases.
Materials and Methods: PDT was used as an adjuvant therapy for the treatment of herpes labialis in four patients. A special type of 0.01% (m/V) of methylene blue solution was applied to the vesicular stage of herpesviral disease and the lesions were irradiated with laser energy (wavelength 660 nm, energy density 120
J/cm2, output power of 40 mW, 2 min per point, 4.8 J of energy/point, at four points). After 24 h the patients
returned and phototherapy was repeated with the same equipment, this time with 3.8 J/cm2 and 15 mW, for
a total dose of 0.6 J. The same procedure was repeated 72 h and 1 wk later.
Results: Treatment with low-level laser therapy can be considered as an option in the treatment of herpes labialis, and decreases the frequency of vesicle recurrence and provides comfort for patients. No significant acute
side effects were noted and the lesions healed rapidly.
Conclusion: Treatment of herpes labialis with PDT was effective, had no side effects, and when associated with
laser phototherapy, accelerated the healing process.
Como referenciar
MAROTTI, JULIANA; ARANHA, ANA C.C.; EDUARDO, CARLOS de P.; RIBEIRO, MARTHA S. Photodynamic therapy can be effective as a treatment for herpes simplex labialis. Photomedicine and Laser Surgery, v. 27, n. 2, p. 357-363, 2009. DOI: 10.1089/pho.2008.2268. Disponível em: http://repositorio.ipen.br/handle/123456789/4871. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.