Synthesis and application of the MCM-41 and SBA-15 as matrices for in vitro efavirenz release study
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Journal of Drug Delivery Science and Technology
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The mesoporous materials in particular the Mobil Composition of Matter No. 41 (MCM-41) and Santa Barbara Amorphous-15 (SBA-15) are considered promising as devices for controlled drug release, because of properties such as hexagonal arrangement, high surface area and non-cytotoxic properties. The materials were synthesized under hydrothermal method and efavirenz (EFZ) was used for testing of controlled release. The material obtained was ordered and had high surface area even after of the incorporation of the drug. The test of the release was made with capsules and the reading was made by UV/Vis with the time interval during two hours to evaluation the efficiency of the dissolution profile of the drug.
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JESUS, R.A.; RABELO, A.S.; FIGUEIREDO, R.T.; CIDES da SILVA, L.C.; CODENTINO, I.C.; FANTINI, M.C.A.; ARAUJO, G.L.B.; ARAUJO, A.A.S; MESQUITA, M.E. Synthesis and application of the MCM-41 and SBA-15 as matrices for in vitro efavirenz release study. Journal of Drug Delivery Science and Technology, v. 31, p. 153-159, 2016. Disponível em: http://repositorio.ipen.br/handle/123456789/25806. Acesso em: 30 Jun 2026.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.