Gamma radiation effects in packaging for sterilization of health products and their constituents paper and plastic film

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Radiation Physics and Chemistry
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The integrity of materials containing packaging (natural or synthetic polymers) is essential to keep the aseptic condition of commercialized products (health care products, food and pharmaceuticals). The objective of this paper was to study gamma radiation effects (25 kGy, 40 kGy and 50 kGy) on the main properties of paper and multilayer films (polyester and polyethylene). Paper and multilayer films are components of packaging (pouches) for radiation sterilization containing medical equipment or products. Paper was the more radiation sensitive among the studied materials and radiation effects were more pronounced at brightness, pH, tearing resistance, bursting strength and tensile strength. Concerning plastic film, no pinholes were induced by radiation and the effects on the tensile strength were not significant. Although the seal strength packaging (pouches) decreased according to increasing dose, the sealing integrity was preserved.

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PORTO, KARINA M.B.G.; NAPOLITANO, CELIA M.; BORRELY, SUELI I. Gamma radiation effects in packaging for sterilization of health products and their constituents paper and plastic film. Radiation Physics and Chemistry, v. 142, p. 23-28, 2018. DOI: 10.1016/j.radphyschem.2016.12.019. Disponível em: http://repositorio.ipen.br/handle/123456789/27902. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.

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