Phantom validation of optical attenuation coefficient estimation model with depth resolution for Optical Coherence Tomography

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dc.contributor.authorAMARAL, MARCELLO M.pt_BR
dc.contributor.authorARAUJO, JEANN C.R.pt_BR
dc.contributor.authorANTUNES, ANDREApt_BR
dc.contributor.authorMONTE, ADAMO F.G.pt_BR
dc.contributor.authorCARA, ANA C.B. dept_BR
dc.contributor.authorFREITAS, ANDERSON Z. dept_BR
dc.contributor.authorZEZELL, DENISE M.pt_BR
dc.coverageNacionalpt_BR
dc.creator.eventoENCONTRO DE OUTONO DA SOCIEDADE BRASILEIRA DE FÍSICA, 42.pt_BR
dc.date.accessioned2019-10-09T18:33:18Z
dc.date.available2019-10-09T18:33:18Z
dc.date.evento26-31 de maio, 2019pt_BR
dc.description.abstractOptical Coherence Tomography (OCT) has been used for imaging and analyzes over a broad number of applications.[1-3] Besides its use for morphological analysis [3] the OCT signal has been used to determine the optical attenuation coe±cient of biological samples for classi¯cation and diagnostic proposes. [1,2] The most common model for estimating the optical attenuation coe±cient based on OCT signal relies on the Lambert- Beers law. It usually assumes a constant attenuation coe±cient value over the image range or over a selected range, losing the in-depth resolution on OCT. Previous published work on literature developed a model to esti- mate the attenuation coe±cient with depth resolution [4], however it assumes that the light is totally attenuated within the image depth range failing for membrane like samples. We present a model that, using the tissue sample transmittance as input, remove this limitation and to estimate the depth-resolved optical attenuation coe±cient. This method allows us to obtain an image of tissue optical properties instead of that from intensity contrast, guiding diagnosis and tissues di®erentiation, extending its application from thin to tick samples. The performance of our method was tested with the assistance of a home built single layer and multi-layer phantoms ( 100¹m each layer). These optical phantoms are composed of a substrate polydimethylsiloxane (PDMS), Zinc- Phthalocyanine (ZnPc) dye as chromophores, and TiO2 as scattering agent. The optical attenuation coe±cient ranges from 0:9 to 2:32 mm¡1, measured using an integrating sphere followed by the Inverse Adding Doubling processing technique. We show that the estimated depth-resolved attenuation coe±cient recovers the reference values, with a error deviation of 7 %.pt_BR
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)pt_BR
dc.description.sponsorshipIDCNPq: INCT 465763/2014-6pt_BR
dc.description.sponsorshipIDCAPES: PROCAD 88881.068505/2014-01pt_BR
dc.event.siglaEOSBFpt_BR
dc.identifier.citationAMARAL, MARCELLO M.; ARAUJO, JEANN C.R.; ANTUNES, ANDREA; MONTE, ADAMO F.G.; CARA, ANA C.B. de; FREITAS, ANDERSON Z. de; ZEZELL, DENISE M. Phantom validation of optical attenuation coefficient estimation model with depth resolution for Optical Coherence Tomography. In: ENCONTRO DE OUTONO DA SOCIEDADE BRASILEIRA DE FÍSICA, 42., 26-31 de maio, 2019, Aracaju, SE. <b>Resumo...</b> São Paulo: Sociedade Brasileira de Física, 2019. Disponível em: http://repositorio.ipen.br/handle/123456789/30217.
dc.identifier.orcid0000-0001-7404-9606pt_BR
dc.identifier.orcid0000-0002-5018-9126pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-7404-9606
dc.identifier.orcidhttps://orcid.org/0000-0002-5018-9126
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/30217
dc.localSão Paulopt_BR
dc.local.eventoAracaju, SEpt_BR
dc.publisherSociedade Brasileira de Físicapt_BR
dc.rightsopenAccesspt_BR
dc.subjecttomography
dc.subjectphantoms
dc.subjectoptical equipment
dc.subjectoptical properties
dc.subjectresolution
dc.subjectimages
dc.subjectcoherence length
dc.subjectcoherent radiation
dc.titlePhantom validation of optical attenuation coefficient estimation model with depth resolution for Optical Coherence Tomographypt_BR
dc.typeResumo de eventos científicospt_BR
dspace.entity.typePublication
ipen.autorDENISE MARIA ZEZELL
ipen.autorANDERSON ZANARDI DE FREITAS
ipen.autorANA CLAUDIA BALLET DE CARA
ipen.codigoautor693
ipen.codigoautor880
ipen.codigoautor9257
ipen.contributor.ipenauthorDENISE MARIA ZEZELL
ipen.contributor.ipenauthorANDERSON ZANARDI DE FREITAS
ipen.contributor.ipenauthorANA CLAUDIA BALLET DE CARA
ipen.date.recebimento19-10
ipen.event.datapadronizada2019pt_BR
ipen.identifier.ipendoc26008pt_BR
ipen.notas.internasResumopt_BR
ipen.type.genreResumo
relation.isAuthorOfPublicationa565f8ad-3432-4891-98c0-a587f497db21
relation.isAuthorOfPublicationa8d821f0-a0a4-4d52-b582-5c5d0afce8f5
relation.isAuthorOfPublication60728d96-5e60-4c76-bbc0-fe03e1c5e0de
relation.isAuthorOfPublication.latestForDiscovery60728d96-5e60-4c76-bbc0-fe03e1c5e0de
sigepi.autor.atividadeZEZELL, DENISE M.:693:920:Npt_BR
sigepi.autor.atividadeFREITAS, ANDERSON Z. de:880:920:Npt_BR
sigepi.autor.atividadeCARA, ANA C.B. de:9257:-1:Npt_BR
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