Phantom validation of optical attenuation coefficient estimation model with depth resolution for Optical Coherence Tomography
Carregando...
Data
Data de publicação
2019
Orientador
Título da Revista
ISSN da Revista
Título do Volume
É parte de
É parte de
É parte de
É parte de
ENCONTRO DE OUTONO DA SOCIEDADE BRASILEIRA DE FÍSICA, 42.
Exportar
Resumo
Optical Coherence Tomography (OCT) has been used for imaging and analyzes over a broad number of
applications.[1-3] Besides its use for morphological analysis [3] the OCT signal has been used to determine the
optical attenuation coe±cient of biological samples for classi¯cation and diagnostic proposes. [1,2] The most
common model for estimating the optical attenuation coe±cient based on OCT signal relies on the Lambert-
Beers law. It usually assumes a constant attenuation coe±cient value over the image range or over a selected
range, losing the in-depth resolution on OCT. Previous published work on literature developed a model to esti-
mate the attenuation coe±cient with depth resolution [4], however it assumes that the light is totally attenuated
within the image depth range failing for membrane like samples. We present a model that, using the tissue
sample transmittance as input, remove this limitation and to estimate the depth-resolved optical attenuation
coe±cient. This method allows us to obtain an image of tissue optical properties instead of that from intensity
contrast, guiding diagnosis and tissues di®erentiation, extending its application from thin to tick samples. The
performance of our method was tested with the assistance of a home built single layer and multi-layer phantoms
( 100¹m each layer). These optical phantoms are composed of a substrate polydimethylsiloxane (PDMS), Zinc-
Phthalocyanine (ZnPc) dye as chromophores, and TiO2 as scattering agent. The optical attenuation coe±cient
ranges from 0:9 to 2:32 mm¡1, measured using an integrating sphere followed by the Inverse Adding Doubling
processing technique. We show that the estimated depth-resolved attenuation coe±cient recovers the reference
values, with a error deviation of 7 %.
Como referenciar
AMARAL, MARCELLO M.; ARAUJO, JEANN C.R.; ANTUNES, ANDREA; MONTE, ADAMO F.G.; CARA, ANA C.B. de; FREITAS, ANDERSON Z. de; ZEZELL, DENISE M. Phantom validation of optical attenuation coefficient estimation model with depth resolution for Optical Coherence Tomography. In: ENCONTRO DE OUTONO DA SOCIEDADE BRASILEIRA DE FÍSICA, 42., 26-31 de maio, 2019, Aracaju, SE. Resumo... São Paulo: Sociedade Brasileira de Física, 2019. Disponível em: http://repositorio.ipen.br/handle/123456789/30217. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.