Methylene blue-mediated antimicrobial photodynamic therapy for canine dermatophytosis caused by Microsporum canis
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Photodiagnosis and Photodynamic Therapy
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Dermatophytosis is a superficial skin infection that widely effects companion animals. Miscrosporum canis is one of the most prevalent species isolated from dogs and cats, and because of the serious zoonotic potential, short-term treatment regimens are preferred to prevent the spread of disease either by direct contact or through contamination of the environment. Antimicrobial photodynamic therapy (APDT) has emerged as a promising strategy able to kill effectively a wide range of pathogens in a short period with minimal morbidity . In this case report, a 7-year-old male dog was diagnosed with dermatophytosis caused by M. canis. Methylene blue-mediated antimicrobial photodynamic therapy (MB-APDT) was applied over the lesions in two sessions with an interval of 7 days. The dog successfully healed, achieving a complete clinical cure after 21 days, without reports of recurrence after a follow-up period of 6 months. Therefore, MB-APDT could be a potential ally of small animal clinicians to treat superficial fungal diseases and should be further explored in Veterinary Medicine.
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CABRAL, FERNANDA V.; SELLERA, FABIO P.; RIBEIRO, MARTHA S. Methylene blue-mediated antimicrobial photodynamic therapy for canine dermatophytosis caused by Microsporum canis: a successful case report with 6 months follow-up. Photodiagnosis and Photodynamic Therapy, v. 36, p. 1-3, 2021. DOI: 10.1016/j.pdpdt.2021.102602. Disponível em: http://repositorio.ipen.br/handle/123456789/32378. Acesso em: 30 Dec 2025.
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