Elemental composition of medicinal plant drugs sold over-the-counter in Sao Paulo city, Brazil
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2010
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INTERNATIONAL SYMPOSIUM ON TRACE ELEMENTS AND MINERALS IN MEDICINE AND BIOLOGY, 4th
Resumo
Medicinal plants have been used to treat diseases
for thousands of years. In Brazil, the use of medicinal
plants is very popular due to the assumption that herbs
which are of natural origin are safe and without side
effects and they are sold over-the-counter. Medicines
derived from medicinal plants are, in general, cheaper
than those from synthetic products and used for selfmedication.
Consequently, it becomes important to
ensure the quality of the plant material and detect
presence of contaminants. Trace elements present in
these plants can also constitute part of active constituents.
In this study neutron activation analysis (NAA)
was applied to evaluate the element composition of
drugs from the plants (Ginseng, Ginkgo biloba, Centella
asiatica, Mulberry and Aloe vera) from different
origins. Samples bought in natural product drugstores
and pharmacies in capsule or tablet forms were ground
to a homogeneous powder. Aliquots of these samples
were irradiated along with synthetic element standards
in the IEA- R1 nuclear research reactor. Short
and long irradiations were carried out for determination
of As, Br, Ca, Co, Cr, Cs, Fe, K, Mn, Na, Rb, Sc, Se, Zn
and lanthanides. The induced gamma activities were
measured using an detector coupled to a gamma
ray spectrometer and the element concentrations
were calculated by the comparative method. Comparisons
made between the results indicated difference
in their element contents depending on the origin of
the sample, as well as, the age of the leaves. Correlations
between the effect of the medicinal plants and
their element content were found for Ca, K and Zn.
Toxic elements such as Hg, Cd, Cu, Sb were not detected.
Arsenic was detected in some samples but at very
low concentrations at the ng/g levels. Biological certified
reference materials were also analyzed for quality
control of the analytical results.
Como referenciar
MOREIRA, H.S.; VASCONCELLOS, M.B.A.; ALVES, E.R.; SANTOS, F.M.; SAIKI, M. Elemental composition of medicinal plant drugs sold over-the-counter in Sao Paulo city, Brazil. In: INTERNATIONAL SYMPOSIUM ON TRACE ELEMENTS AND MINERALS IN MEDICINE AND BIOLOGY, 4th, June, 9-12, 2010, Saint Petersburg, Russia. Abstract... p. 12. Disponível em: http://repositorio.ipen.br/handle/123456789/21134. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.