Influence of silicon, strontium and aluminum oxides on silicon nitride ceramics for bone replacements
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Although silicon nitride ceramics have been shown very propitious to be used for bone replacements, some
characteristics can be controlled to improve their osseointegrations process. One of them is the intergranular
phase whose composition can be specified to stimulate mineralization and osteoblastic production. In this
paper, the intergranular glassy phase was projected in order to contain silicon, strontium and aluminum oxides.
Silicon nitride samples containing different contents of SiO2, SrO and Al2O3 were sintered at 1815oC for
1 hour and characterized by scanning electron microscopy and X-ray diffraction. Hardness and fracture
toughness were determined by Vickers hardness test and compressive strength was evaluated using an universal
material testing machine. The biological behavior was studied in regard to cytotoxicity and cell proliferation
by means of in vitro experiments. The samples reached high densities (higher than 95 %TD), total
α→β-Si3N4 transformation, fracture toughness higher than 6.5 MPa.m1/2, compressive strength up to 2500
MPa and Vickers hardness less than 9.8 GPa. All samples were non-cytotoxic and able to promote cell proliferation
with great potential to be used as components for bone replacements. However, that sample with
high content of strontium had the best results of cell proliferation, proving the importance of a careful choice
of intergranular phase composition in silicon nitride ceramics.
Como referenciar
NASCIMENTO, SERGIO F. do; RODAS, ANDREA C.D.; CARVALHO, FLAVIO M. de S.; HIGA, OLGA Z.; SILVA, CECILIA C.G. e. Influence of silicon, strontium and aluminum oxides on silicon nitride ceramics for bone replacements. Revista Matéria, v. 25, n. 4, 2020. DOI: 10.1590/S1517-707620200004.1178. Disponível em: http://200.136.52.105/handle/123456789/31662. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.