Colorectal Adenocarcinoma
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Current Pharmaceutical Design
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Background: Adenocarcinoma of colon and rectum are one of the most common cancers worldwide,
responsible for over 1,300,000 people diagnosed. Also, they are responsible for metastasis, which leads to death
in less than 5 years.
Methods: In this study, we developed, characterized, and pre-clinically tested a new nano-radiopharmaceutical
for early and differential detection of adenocarcinoma of colon and rectum.
Results and Conclusion: Results demonstrated the specificity of the developed nanosystem and the ability to
reach the tumor with very specific targeting. Also, the imaging data support the use of this nano-agent as a nanoimaging-
guided-radiopharmaceutical.
Como referenciar
ALMEIDA JUNIOR, JULIO C. de; HELAL-NETO, EDWARD; PINTO, SUYENE R.; SANTOS, SOFIA N. dos; BERNARDES, EMERSON S.; AL-QAHTANI, MOHAMMED; NIGRO, FIAMMETTA; ALENCAR, LUCIANA M.R.; RICCI-JUNIOR, EDUARDO; SANTOS-OLIVEIRA, RALPH. Colorectal Adenocarcinoma: imaging using 5-Fluoracil nanoparticles labeled with technetium 99 metastable. Current Pharmaceutical Design, v. 25, n. 30, p. 3282-3288, 2019. DOI: 10.2174/1381612825666190816235147. Disponível em: http://repositorio.ipen.br/handle/123456789/30823. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.