Colorectal Adenocarcinoma

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dc.contributor.authorALMEIDA JUNIOR, JULIO C. dept_BR
dc.contributor.authorHELAL-NETO, EDWARDpt_BR
dc.contributor.authorPINTO, SUYENE R.pt_BR
dc.contributor.authorSANTOS, SOFIA N. dospt_BR
dc.contributor.authorBERNARDES, EMERSON S.pt_BR
dc.contributor.authorAL-QAHTANI, MOHAMMEDpt_BR
dc.contributor.authorNIGRO, FIAMMETTApt_BR
dc.contributor.authorALENCAR, LUCIANA M.R.pt_BR
dc.contributor.authorRICCI-JUNIOR, EDUARDOpt_BR
dc.contributor.authorSANTOS-OLIVEIRA, RALPHpt_BR
dc.coverageInternacionalpt_BR
dc.date.accessioned2020-02-21T15:35:33Z
dc.date.available2020-02-21T15:35:33Z
dc.date.issued2019pt_BR
dc.description.abstractBackground: Adenocarcinoma of colon and rectum are one of the most common cancers worldwide, responsible for over 1,300,000 people diagnosed. Also, they are responsible for metastasis, which leads to death in less than 5 years. Methods: In this study, we developed, characterized, and pre-clinically tested a new nano-radiopharmaceutical for early and differential detection of adenocarcinoma of colon and rectum. Results and Conclusion: Results demonstrated the specificity of the developed nanosystem and the ability to reach the tumor with very specific targeting. Also, the imaging data support the use of this nano-agent as a nanoimaging- guided-radiopharmaceutical.pt_BR
dc.format.extent3282-3288pt_BR
dc.identifier.citationALMEIDA JUNIOR, JULIO C. de; HELAL-NETO, EDWARD; PINTO, SUYENE R.; SANTOS, SOFIA N. dos; BERNARDES, EMERSON S.; AL-QAHTANI, MOHAMMED; NIGRO, FIAMMETTA; ALENCAR, LUCIANA M.R.; RICCI-JUNIOR, EDUARDO; SANTOS-OLIVEIRA, RALPH. Colorectal Adenocarcinoma: imaging using 5-Fluoracil nanoparticles labeled with technetium 99 metastable. <b>Current Pharmaceutical Design</b>, v. 25, n. 30, p. 3282-3288, 2019. DOI: <a href="https://dx.doi.org/10.2174/1381612825666190816235147">10.2174/1381612825666190816235147</a>. Disponível em: http://repositorio.ipen.br/handle/123456789/30823.
dc.identifier.doi10.2174/1381612825666190816235147pt_BR
dc.identifier.fasciculo30pt_BR
dc.identifier.issn1381-6128pt_BR
dc.identifier.orcid0000-0002-0029-7313pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-0029-7313
dc.identifier.percentilfi33.889pt_BR
dc.identifier.percentilfiCiteScore69.50
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/30823
dc.identifier.vol25pt_BR
dc.relation.ispartofCurrent Pharmaceutical Designpt_BR
dc.rightsclosedAccesspt_BR
dc.subjectcarcinomas
dc.subjectneoplasms
dc.subjectnanoparticles
dc.subjectpolymerization
dc.subjectradiopharmaceuticals
dc.subjectimages
dc.subjectfluorouracils
dc.subjecttechnetium 99
dc.subjectdrugs
dc.titleColorectal Adenocarcinomapt_BR
dc.typeArtigo de periódicopt_BR
dspace.entity.typePublication
ipen.autorEMERSON SOARES BERNARDES
ipen.autorSOFIA NASCIMENTO DOS SANTOS
ipen.codigoautor12099
ipen.codigoautor14464
ipen.contributor.ipenauthorEMERSON SOARES BERNARDES
ipen.contributor.ipenauthorSOFIA NASCIMENTO DOS SANTOS
ipen.date.recebimento20-02
ipen.identifier.fi2.208pt_BR
ipen.identifier.fiCiteScore5.1
ipen.identifier.ipendoc26648pt_BR
ipen.identifier.iwosWoSpt_BR
ipen.identifier.ods3
ipen.range.fi1.500 - 2.999
ipen.range.percentilfi25.00 - 49.99
ipen.subtituloimaging using 5-Fluoracil nanoparticles labeled with technetium 99 metastablept_BR
ipen.type.genreArtigo
relation.isAuthorOfPublication8115c8bd-822c-4f5a-9f49-3c12570ed40a
relation.isAuthorOfPublicationab78881a-78eb-42be-a463-aaf80e70de3d
relation.isAuthorOfPublication.latestForDiscoveryab78881a-78eb-42be-a463-aaf80e70de3d
sigepi.autor.atividadeBERNARDES, EMERSON S.:12099:110:Npt_BR
sigepi.autor.atividadeSANTOS, SOFIA N. dos:14464:110:Npt_BR

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