A novel rectal applicator for contact radiotherapy with HDR 192Ir sources
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Brachytherapy
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PURPOSE: Dose escalation to rectal tumors leads to higher complete response rates and may
thereby enable omission of surgery. Important advantages of endoluminal boosting techniques
include the possibility to apply a more selective/localized boost than using external beam radiotherapy.
A novel brachytherapy (BT) rectal applicator with lateral shielding was designed to be used
with a rectoscope for eye-guided positioning to deliver a dose distribution similar to the one of contact
x-ray radiotherapy devices, using commonly available high-dose-rate 192Ir BT sources.
METHODS AND MATERIALS: A cylindrical multichannel BT applicator with lateral shielding
was designed by Monte Carlo modeling, validated experimentally with film dosimetry and
compared with results found in the literature for the Papillon 50 (P50) contact x-ray radiotherapy
device regarding rectoscope dimensions, radiation beam shape, dose fall-off, and treatment time.
RESULTS: The multichannel applicator designed is able to deliver 30 Gy under 13 min with a
20350 U (5 Ci) source. The use of multiple channels and lateral shielding provide a uniform circular
treatment surface with 22 mm in diameter. The resulting dose fall-off is slightly steeper (maximum
difference of 5%) than the one generated by the P50 device with the 22 mm applicator.
CONCLUSIONS: A novel multichannel rectal applicator for contact radiotherapy with high-doserate
192Ir sources that can be integrated with commercially available treatment planning systems
was designed to produce a dose distribution similar to the one obtained by the P50 device.
Como referenciar
BELLEZZO, MURILLO; FONSECA, GABRIEL P.; VERRIJSSEN, AN-SOFIE; VONCKEN, ROBERT; BOSCH, MICHIEL R.V. den; YORIYAZ, HELIO; RENIERS, BRIGITTE; BERBEE, MAAIKE; LIMBERGEN, EVERT J.V.; VERHAEGEN, FRANK. A novel rectal applicator for contact radiotherapy with HDR 192Ir sources. Brachytherapy, v. 17, n. 6, p. 1037-1044, 2018. DOI: 10.1016/j.brachy.2018.07.012. Disponível em: http://repositorio.ipen.br/handle/123456789/29271. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.