Effect of low-intensity therapy on mast cell degranulation in human oral mucosa

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Lasers in Medical Science
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Little is known about the physiological mechanisms related to low-intensity laser therapy (LILT), particularly in acute inflammation and subsequent wound healing. The objective of this study was to verify the effect of LILT on mast cell degranulation. Epulis fissuratum tissues from eight patients were used. One part of the lesion was irradiated with an AsGaAl laser (λ= 670 nm, 8.0 J/cm2, 5 mW, 4 min). The other part was not irradiated. Then, the specimens were immediately removed, fixed and examined by light microscopy. The number of mast cells was similar in laser-treated samples when compared with non-irradiated specimens. The degranulation indexes of the mast cells observed in the irradiated samples were significantly higher than those of controls (P<0.05). LILT with the parameters used increased the number of degranulated mast cells in oral mucosa.

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SAWAZAKI, IRIS; MARTINS, VINICIUS R.G.; RIBEIRO, MARTHA S.; MARQUES, MARCIA M. Effect of low-intensity therapy on mast cell degranulation in human oral mucosa. Lasers in Medical Science, v. 24, n. 1, p. 113-116, 2009. DOI: 10.1007/s10103-007-0531-1. Disponível em: http://repositorio.ipen.br/handle/123456789/4870. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.

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