Progress in clinical diagnosis using neutrons and X-rays
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2024
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ENCONTRO DE PRIMAVERA DA SOCIEDADE BRASILEIRA DE FISICA, 4.
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Understanding potential trajectories in health is crucial for guiding long-term policy
in the health area. This study provides alternative approaches to clinical practices
(dosage of ions and metal) using neutrons and X-rays. In recent years, Neutron
Activation Analysis (NAA) and X-ray Fluorescence (XRF) techniques have been
applied to this clinical end at IPEN/SP- Brazil, in collaboration with research centers.
These analytical techniques have been applied to investigate specific ions and metal
in biological samples, in-vitro (serum, blood, urine, saliva) and in-vivo (nails and
hair), for monitoring and diagnosis of prevalent diseases in Brazil. The NAA
measurements were performed using the IEA-R1 nuclear reactor at IPEN
(CNEN/SP-Brazil) and XRF data were obtained using a compact X-ray spectrometer
(X-123 SDD, Amptek®) with Ag, Au, and Rh targets. There are several motivations
and positive expectations for the use of these alternatives for diagnosis, but the great
advantage is the feasibility of using the X-ray experimental set-up facility, outside the
nuclear reactor premises, which allows its use in underserved regions without a
clinical laboratory. In addition, we provide a robust platform of reference values in
biological samples (serum, blood, urine, saliva) that can be explored or implemented
by other analytical techniques. We intend to stimulate the biochemical analysis of
body fluids as well as in-vivo samples (nails and hair) using a compact and portable
X-ray spectrometer setup.
Como referenciar
GOES, MARIA P. de O.; BENEDITO, MARIA G.M.; MOURA, LARISSA A.S.; OLIVEIRA, CLEBER D. de; GIOVANNI, DALTON; ZAMBONI, CIBELE B. Progress in clinical diagnosis using neutrons and X-rays. In: ENCONTRO DE PRIMAVERA DA SOCIEDADE BRASILEIRA DE FISICA, 4., 24-27 de setembro, 2024, Belo Horizonte, MG. Resumo... São Paulo, SP: Sociedade Brasileira de Física - SBF, 2024. Disponível em: https://repositorio.ipen.br/handle/123456789/49140. Acesso em: 20 Jan 2026.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.