Development of radioactive nanoparticles functionalized with gum arabic to be used in nanobrachytherapy
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2023
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BRAZIL MRS MEETING, 21st
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The development of new materials emerges as an alternative to the treatment of cancer,
from the combination of nanotechnology and brachytherapy a new area of research was
born, Nanobrachytherapy, which through the properties of nanometric materials can
achieve better results in the fight against cancer. The objective of this work is classified as
radiotherapy, which consists of the use of ionizing radiation to destroy or inhibit the growth
of abnormal cells that form a tumor. [1] The ability to integrate NPsAu into biological
systems is due to the nanometric dimensions of NPsAu probes which facilitate their
incorporation into biological systems, as well as their bioconjugation and non-cytotoxic
potential. [2] Taking into account the previous objective, gold was selected as the base
element for obtaining nanometric systems, which due to its chemical richness and especially
due to the intrinsic properties of one of its radioisotopes, which would allow us in theory to
meet the stated objective. . Initially, it was based on the knowledge of the literature, and
non-radioactive nanometric systems were obtained, and after a series of stability,
characterization and application tests, the radioactive nanometric systems were obtained.
Working with radioactive systems posed a great challenge, and up to now it presents us
with situations to solve, but we have managed to create a methodology for obtaining,
characterizing and applying radioactive gold nanoparticles, and also obtaining positive
results from their application.
Como referenciar
ROSERO, WILMMER A.A.; BARBEZAN, ANGELICA B.; RIGO, MARIA E.Z.; RODRIGUES, PRISCILA S.; TEODORO, LARA E.H.; TALACIMON, CRISTHIAN F.; ZEITUNI, CARLOS A.; ROSTELATO, MARIA E.C.M. Development of radioactive nanoparticles functionalized with gum arabic to be used in nanobrachytherapy. In: BRAZIL MRS MEETING, 21st, October 1-5, 2023, Maceió, AL. Abstract... São Carlos, SP: Aptor Software, 2023. p. 553-553. Disponível em: http://repositorio.ipen.br/handle/123456789/34559. Acesso em: 24 Mar 2026.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.