Childhood exposure to diagnostic X-ray ionizing radiation and leukemia risk
Carregando...
Data
Data de publicação
2025
Orientador
Título da Revista
ISSN da Revista
Título do Volume
É parte de
É parte de
É parte de
É parte de
RADIOLOGICAL SOCIETY OF NORTH AMERICA
Exportar
Resumo
IntroductionLeukemia is the most common cancer in children, and many studies have suggested a possible causal relationship with childhood exposure to x-ray ionizing
radiation.ObjectiveTo assess the risk of developing leukemia in pediatric patients exposed to diagnostic x-ray ionizing radiation.Methods: A systematic review of the
literature was conducted. Electronic databases searched included PubMed, EMBASE, Web of Science. We included peer-reviewed publications of cohort and case-control
studies involving pediatric patients exposed to diagnostic x-ray ionizing radiation, evaluating the risk of these patients developing leukemia.Two reviewers analyzed the
selected abstracts and full-text articles,performed data extraction,and evaluated the methodological quality of the selected articles.The methodological quality was
assessed according to the Newcastle- Ottawa Scale. A meta-analysis was conducted using RevMan.ResultsOut of the 330 citations screened, 8 publications were
included, representing 6,721 cases and 12,730 controls.All studies were designed as case-control.Age varied from 0 to 14 years,with a predominance of boys.The
studies presented good methodological quality, but the results from individual studies were controversial.The summary of results demonstrated significant positive
associations for being exposed to one or more, and three or more x-rays and the subsequent development of leukemia. No significant association was identified when
considering four or more x-rays.
Como referenciar
RODRIGUES, GUILHERME O.; SOUZA, CARLA D. de; ROSTELATO, MARIA E.C.M.; FERREIRA, HORTENCIA H.J.; SANTANA, MARCOS R. Childhood exposure to diagnostic X-ray ionizing radiation and leukemia risk: a rapid systematic review of literature and meta-analysis. In: RADIOLOGICAL SOCIETY OF NORTH AMERICA, November 30 - December 4, 2025, Chigado, USA. Abstract... Chigado: , 2025. Disponível em: https://repositorio.ipen.br/handle/123456789/49921. Acesso em: 25 May 2026.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.