DALTON GIOVANNI NOGUEIRA DA SILVA

DALTON GIOVANNI NOGUEIRA DA SILVA

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Propostas alternativas para o conhecimento e uso da Energia Nuclear
2022 - ZAMBONI, C.B.; GIOVANNI, D.N.S.; KOKA, A.C.; ALMEIDA, M.R.; MEDEIROS, I.M.M.A.; LEAO, A.R.
Sodium analysis in sweeteners by neutron activation analyses technique
2019 - MEDEIROS, I.M.M.A.; ZAMBONI, C.B.; GIOVANNI, D.N.S.; MEDEIROS, J.A.G.
Evaluation of Sodium in sweeteners is important in nutritional investigations and for consumers: excessive sodium consumption is one of the major risk factors, responsible for hypertension and cardiovascular diseases. In this study, twelve brands acquired in markets of São Paulo city were analysed by Instrumental Neutron Activation Analyses technique (INAA). The aim was to verify compliance with ANVISA recommendation in relation to sodium level. The results were compared with the amounts recommended and with the tolerable intake limit (< 0.4 g/kg). The sodium concentration in sweeteners samples showed low content for most of the brands. The results shown that for the general population, it is not risk.
Investigation of elements in sweeteners by NAA analytic technique
2019 - MEDEIROS, ILCA M.M.A.; ZAMBONI, CIBELE B.; GIOVANNI, DALTON N.S.; MEDEIROS, JOSÉ A.G. de
In this study, brands of sweeteners (aspartame and sucralose) marketed in Brazil were investigated by Neutron Activation Analysis (NAA). The measurements were performed using the IEA-R1 nuclear reactor at IPEN - CNEN/SP. The elements Cl and Na were identified in all samples. The Na concentration in sweeteners samples showed low content for most of the brands (0.013 –3.81 g kg-1), while Cl had high concentration variation (0.04 – 11.10 g kg-1). These data provide knowledge regarding nutritional aspect and toxicity derived from sweetener consumption.
Neutron activation analyses for investigation of antilonomic serum for caterpillars lonomia obliqua walker (Lepidoptera: saturniidae)
2017 - LEAO, A.R.; ZAMBONI, C.B.; SILVA, D.G.N. da; MEDEIROS, I.M.M.A.; SIMONS, S.M.
Since 1996 the Butantan Institute (IBu, São Paulo city), in collaboration with the Health Departments of some Brazilian states, produces serum antilonomic using the caterpillars of the species L. obliqua from several regions of Brazil. However, no data of their elemental composition to ensure that the antivenom produced (considering the different origins) maybe used to manufacture serum unchanged in the final product, as regards the toxicity of inorganic elements. In this investigation, we intend to check the elemental characterization of this antidote using Neutron Activation Analyses technique (NAA). The NAA measurements were performed in the IEA-R1 nuclear reactor (IPEN/CNEN-SP, Brasil). Each sample was irradiated for 120s and gamma counting endured 300s, HPGe detector (ORTEC-GEM 60195) coupled to a MCA (ORTEC - 919E) used. The elements concentration were obtained using the ATIVAÇÃO software. These quantitative analysis of the antilonomic serum will generate data to evaluate the possibility of establishing a standard extract, which would reduce costs in the antilonomic serum production process, as well as improvements in serum production process antilonomic in the Butantan Institute, meeting the standards of good manufacturing practices and good laboratory practice.
Quantification of Cl and Na in the antigen used for the production of serum antilonomic
2016 - LEAO, A.R.; ZAMBONI, C.B.; SILVA, D.G.N.; MEDEIROS, I.M.M.A.; WEN, F.H.; ALINE, A.V.; MENDONÇA, R.Z.; SIMONS, S.M.
Neutron Activation Analyses for investigation of antilonomic serum for caterpillars Lonomia obliqua Walker (Lepidoptera: Saturniidae)
2016 - LEAO, ANICARINE R.; ZAMBONI, CIBELE B.; SILVA, DALTON G.N. da; MEDEIROS, ILCA M.M.A.; WEN, FAN H.; MENDONÇA, RONALDO Z.; SIMONS, SIMONE M.
Since 1996 the Butantan Institute (IBu, São Paulo city), in collaboration with the Health Departments of some Brazilian states, produces serum antilonomic using the caterpillars of the species L. obliqua from several regions of Brazil. However, no data of their elemental composition to ensure that the antivenom produced (considering the different origins) may be used to manufacture serum unchanged in the final product, as regards the toxicity of inorganic elements. In this investigation, we intend to check the elemental characterization of this antidote using Neutron Activation Analyses technique (NAA). The NAA measurements were performed in the IEA-R1 nuclear reactor (IPEN/CNEN-SP, Brasil). Each sample was irradiated by 120s and gamma counting by 300s using HPGe detector (ORTEC-GEM 60195) coupled to a MCA (ORTEC - 919E). The elements concentration were obtained using the ATIVAÇÃO software. These quantitative analyzes of the antilonomic serum will generate data to evaluate the possibility of establishing a standard extract, which would reduce costs in the antilonomic serum production process, as well as improvements in serum production process antilonomic in the Butantan Institute, meeting the standards of good manufacturing practices and good laboratory practice.